cardiomyopathy Tag

02 Jan Multiscale modeling of left ventricle

Posted at 18:22h in Multiscale heart modeling, Stories 0 Comments

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Multiscale modeling of left ventricleIn silico clinical trials are the future of medicine and virtual testing and simulation are the future of medical engineering. The use of a computational platform can reduce the costs and time required for developing new models of medical devices and...

02 Jan Predicting the effects of drugs that affect changes in kinetic parameters

Posted at 18:17h in Drug testing and discovery, Stories 0 Comments

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MavacamtenMavacamten (MYK-461) was recently approved by FDA as an allosteric inhibitor of sarcomeric myosins since it had been successfully used in clinical trials for treatment of obstructive HCM. Mavacamten negative inotropic action is likely mediated by the shift of detached motor heads towards auto inhibited...

cardiomyopathy Tag

02 Jan Multiscale modeling of left ventricle

02 Jan Predicting the effects of drugs that affect changes in kinetic parameters

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